Steroid pulse therapy for Kawasaki disease unresponsive to additional immunoglobulin therapy
نویسندگان
چکیده
منابع مشابه
Steroid Pulse Therapy for Kawasaki Disease Complicated with Myocarditis.
BACKGROUND The clinical management of intravenous immunoglobulin-resistant Kawasaki disease shock syndrome (KDSS) is obscure. CASE CHARACTERISTICS Three children presented with intravenous immunoglobulin-resistant KDSS complicated with myocarditis. OUTCOME All cases were successfully managed with steroid pulse therapy. MESSAGE Steroid pulse therapy is effective in immunoglobulin-resistant...
متن کاملAntimicrobial therapy using sulfamethoxazole trimethoprim for Kawasaki disease patients unresponsive to intravenous immunoglobulin
Our previous study suggested that the production of superantigens and heat-shock protein 60 by small intestinal bacteria might play a role in Kawasaki disease (KD). We demonstrated that they were all resistant to commonly used antibiotics, except for sulfamethoxazole trimethoprim (SMX-TMP). We used SMX-TMP for 7 cases of KD that were unresponsive to intravenous immunoglobulin (IVIG) and studied...
متن کاملPredictors of nonresponse to intravenous immunoglobulin therapy in Kawasaki disease
PURPOSE It has been reported that 10% to 20% of children with Kawasaki disease (KD) will not respond to intravenous immunoglobulin (IVIG) treatment. In this study, we aimed to identify useful predictors of therapeutic failure in children with KD. METHODS We examined 309 children diagnosed with KD at the Kyungpook National University Hospital and the Inje University Busan Paik Hospital between...
متن کاملMethylprednisolone pulse therapy for massive lymphadenopathy in a child with intravenous immunoglobulin-resistant Kawasaki disease.
Kawasaki disease (KD) is an acute febrile multi-system vasculitis of unknown etiology. The diagnosis is based on clinical features. We describe a case of intravenous immunoglobulins (IVIG)-resistant KD presenting with persistent fever and massive cervical lymphadenopathy associated with mild respiratory distress. The symptoms resolved after methylprednisolone pulse therapy. High-dose pulse ster...
متن کاملIntravenous immunoglobulin therapy for older children with Kawasaki disease
The risk-benefit balance of the full dose intravenous immunoglobulin (IVIG) infusion of 2 g/kg body weight/dose in older children has not been established. In this study, I investigated the safety and efficacy of this therapy for older children. In total, I recruited 210 children who had received 2 g/kg/dose of IVIG therapy for Kawasaki disease between 1999 and 2015 at the Department of Pediatr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Paediatrics & Child Health
سال: 2011
ISSN: 1205-7088,1918-1485
DOI: 10.1093/pch/16.8.479